The etiology of CP is very diverse and multifactorial. The causes are congenital, genetic, inflammatory, infectious, anoxic, traumatic and metabolic. The injury to the developing brain may be prenatal, natal or postnatal. As much as 75% – 80% of the cases are due to prenatal injury with less than 10% being due to significant birth trauma or asphyxia.5 The most important risk factor seems to be prematurity and low birth weight with risk of CP increasing with decreasing gestational age and birth weight. Cerebral palsy is seen in 10 – 18 % of babies in 500–999 grams birth weight.6 CP occurs more commonly in children who are born very prematurely or at term. Although term infants are at relatively low absolute risk, term births constitute the large majority of all births, as well as approximately half of all births of children with cerebral palsy. Prenatal maternal chorioamnionitis is also a significant risk factor accounting for as much as 12% of cerebral palsy in term infants and 28% in premature infants.7, 8 Cystic periventricular leukomalacia (CPVL) is a risk factor with 60%-100% of patients with CPVL developing CP.8  Read more here  Cerebral Palsy Risk  Factors